STUDY SUMMARIES

CONCENTRATED FIBRIN (DISCSEEL® PROCEDURE) STUDY SUMMARIZES DISC PAIN:

  • Disc pain is among the largest sources of low back pain
  • No conservative or non-surgical therapy, including physical therapy, is scientifically proven to relieve disc pain
  • Long term surgical success is less than 50%

CAUSES OF DISC DEGENERATION:

  • Vertebral endplate sclerosis
  • Accumulation of painful and damaging inflammatory proteins and proteolytic enzymes
  • Nucleus Pulposis death
  • Disc reduction in proteoglycan and water content
  • Nucleus Pulposis fibrosis

CHRONIC DISC PAIN IS ASSOCIATED WITH:

  • Accumulation of radial and concentric anulus fibrosis tears
  • Vascular and painful nerve in-growth into anular tears
  • Increased sensitivity to pain stimuli of exposed nerves

CHARACTERISTICS OF THE DISCSEEL® PROCEDURE:

  • The Biologic flows into the disc’s tears and fissures, thus sealing them with a resorbable tissue matrix
  • Concentrated fibrin (Discseel® Procedure) is uniquely formulated for disc healing

HEALING WITH CONCENTRATED FIBRIN:

  • Builds a naturally conductive tissue scaffold
  • Metabolically reduces inflammation
  • Improves anabolic catabolic balance
  • Enhanced disc healing by concentrated fibrin

PAIN RELIEF RESULTING FROM CONCENTRATED FIBRIN (DISCSEEL® PROCEDURE):

  • Concentrated fibrin binds to degenerated disc tissue, sealing anular leaks
  • Inhibits inflammatory cytokines and proteolytic enzymes
  • Pre-programmed degradation of concentrated fibrin stimulates tissue repair via chemotaxis
  • The disc tissue repair provides sustained pain relief

CONCLUSION:

  • THe FDA study proves concentrated fibrin heals degenerated discs
  • Catalyze the natural soft tissue repair process
  • The Discseel® Procedure is a non-surgical, percutaneous procedure
  • Unlike fusions or artificial discs, Discseel® Procedure does not damage adjacent discs.
  • FDA NASS Outstanding Study of the Year supports concentrated fibrin used in the Discseel® Procedure beneficial physical and metabolic modes of action
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