Fibrin is an FDA-approved drug made by Baxter and Johnson&Johnson. It is the natural molecule that heals skin cuts by regrowing skin. Fibrin also causes disc tissue to heal and regrow. Fibrin is the only drug or biologic proven to regrow human discs.  People cannot be allergic to fibrin because fibrin is naturally found in every human, because this would be analogous to being allergic to water or calcium; A person cannot be allergic to water or calcium because water and calcium is in every human, just like fibrin. 

Like many drugs, fibrin is obtained from human blood plasma. Fibrin has been used for several decades, on tens of thousands of people with zero incidence of transmitting pathogens because it is a highly purified molecule. 

Fibrin binds to damaged discs because it is a strong bio adhesive glue sealant, and this property allows fibrin to remain in discs and heal them while stem cells or PRP fail, because they leak and cannot bind to damaged disc tissue.

Yes, fibrin is an FDA approved drug. The FDA allows the use of fibrin in spinal discs. The first indication approved for fibrin by the FDA was to use in the Spinal Canal to seal dura tears and cuts caused by spinal surgeons.

Fibrin heals discs the same way fibrin naturally heals skin cuts and other injured tissue. (In comparison, stem cells and PRP cannot heal discs, because they lack fibrin’s properties.)

(Fasten your seatbelts…although you will recognize the healing process is simple.)

When a person’s skin is cut or damaged, it exposes amino acid chains. Next, the two natural molecules always flowing in the bloodstream recognize the damaged skin’s exposed amino acid chains and bind to them at the injury site to seal and heal the damage.  When these two molecules come together at the injury site, they form fibrin, a strong adhesive sealant. This fibrin sealant is a 3-dimentional matrix that serves as a foundation causing new skin growth. During the following weeks, fibrin branches intentionally break away, and are replaced with normal skin tissue molecules. (In the disc, they are replaced with normal disc tissue molecules in the same manner.) This is the natural “healing process.” (In comparison, after surgery, discs don’t heal with normal tissue, and so discs continuously re-tear to cause recurrent disc herniations.  Whereas the Discseel® Procedure causes strong , normal disc tissue growth.

“For Geeks:“ 

The healing process:

The two natural molecules mentioned above, flow in everyone’s bloodstream and are called “prothrombin” and “fibrinogen.” When they sense exposed amino acid chains of injured tissue and come together, “prothrombin molecule”  causes “fibrinogen” to become fibrin, a natural adhesive sealant. Fibrin is a “polymer” comprised of small branches (called monomers) which break away, to be replaced with normal skin tissue. In the disc, they are replaced with normal disc tissue.

Annular tears are the true, underlying cause of all disc problems, including disc herniation, bulge, degeneration, protrusion, pinched nerve, prolapsed disc…all result from Annular tears.

Ironically, Annular tears are rarely mentioned because, prior to the Discseel® Procedure, no treatment existed to repair Annular tears. 

Annular tears are tears of the Annulus Fibrosus. The Annulus Fibrosus is the 17 layers which encircles the center Nuclues Pulposus gel and contains pain nerves within its layers. When Annular tears allow gel to leak outwards, the gel is “perceived” as a “foreign substance” by the human body and causes inflammation of the Annular layers, which is the true cause of low back pain (or neck pain.) If there’s many Annular tears, they allow gel to leak entirely outwards onto Spinal Nerves adjacent to discs, causing inflammation of Spinal nerves. Spinal nerve inflammation is called “radiculopathy” (aka sciatica.) and so radiculopathy is caused by Spinal Nerve inflammation and not by “pinched nerves” as was once thought. This explains why epidural steroids occasionally provide temporary relief. However, if discs continue leaking through Annular tears, they need the Discseel® Procedure to repair Annular tears.

Congress granted special patent protection to the Discseel® Procedure because it deemed in worthy of protection, while no other Regenerative Medicine procedure was deemed worthy of protection.

Specifically, for the good of Mankind, the United States Congress proclaimed: “No medical procedure may be patented because medical procedures are for the good of Mankind.” Thus, although Congress allows drugs or medical devices to be patented, (to incentivize their research) it does not allow procedures to be patented. 

However, it was acknowledged that Regenerative Medicine has the potential to provide the greatest advancements in healthcare, and so Congress passed a Congressional Act stating that a procedure may be patented only if it can cause the regrowth of new tissue and healing. 

Only the Discseel® Procedure meets this strict criterion by healing spinal discs, and so only the Discseel® Procedure is patented. No other Regenerative Medicine procedure meets these criteria and so no other procedure (including not PRP, not stem cells) can be patented.

A herniated disc, (sometimes wrongly referred to as a “slipped disc” or “ruptured disc.”  Herniation occurs after the outer portion of a disc, the Annulus Fibrosus, tears, causing the inner portion, the Nucleus Pulposus gel, to leak outwards. When the gel flows through the disc and contacts the Spinal Nerve, the spinal nerves become inflamed. The inflamed disc and spinal nerve cause low back pain and sciatica leg pain, numbness, and weakness (radiculopathy.) Symptoms often increase and decrease, proving that its liquid inflammation and not a pinched nerve, as was once wrongly believed.