The DISCSEEL® Procedure is the only spine regenerative procedure that has been awarded patents by the U.S. Patent and Trademark Office. As the inventor of the DISCSEEL Procedure, Dr. Pauza has thus far earned 16 medical technology patents, with more than a dozen patent applications pending.
Abstract: A method of repairing a defect in an annulus fibrosus of an intervertebral disc, without excising the entire nucleus pulposus of the disc with an in situ curable, bio-compatible polymerizable or polymeric material, wherein at least one of said components is a cross linkable material and at least one other of said components is a cross linking agent for said cross linkable material.
Inventor: Kevin Pauza
Abstract: A biologic preparation (tissue adhesive) comprising fibrinogen, thrombin and a corticosteroid agent, wherein a solution containing the corticosteroid treatment agent is used to reconstitute the thrombin from a freeze-dried state.
Inventor: Kevin Pauza
Abstract: A biologic preparation (tissue adhesive) for injection into a human body comprising fibrinogen, thrombin and a corticosteroid agent.
Inventor: Kevin Pauza
A. A method for delivering a biological tissue adhesive for injection in a human body comprising fibrinogen, thrombin and a corticosteroid agent.
B. A method for delivering a biological tissue adhesive for injection in a human body comprising: providing a spinal needle, a dual syringe, a freeze-dried fibrinogen component, a freeze-dried thrombin component, and a betamethasone-containing solution to form a system for delivering a biological tissue adhesive.
Inventor: Kevin Pauza
A. A system for delivering a biological tissue adhesive, comprising: a fibrinogen component; a thrombin component, and a corticosteroid-containing solution.
B. A system for delivering a biological tissue adhesive, comprising: a fibrinogen component; a thrombin component, and a corticosteroid-containing solution, a spinal needle; and a dual syringe.
Inventor: Kevin Pauza
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Grant
Filed: August 17, 2005
Issued: October 6, 2009
Assignee: Spinal Restoration, Inc.
Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
A. A device for delivery of biologic materials, comprising a cartridge having at least two cylinder bores for fluids of the biologic materials to be delivered.
B. A kit for treating a disc, comprising: fibrinogen, thrombin, and a device for delivery of biologic materials.
Inventor: Kevin Pauza
A. The invention includes a method for treating a disc of a patient using a tissue sealant comprising a snake venom to convert the fibrinogen to fibrin and at least one supplement.
B. Supplements include a long “laundry list” of possible additives.
Inventor: Kevin Pauza
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Grant
Filed: August 17, 2005
Issued: June 26, 2012
Assignee: Spinal Restoration, Inc.
Inventors: Brian D. Burkinshaw, Steven I. Whitlock, Kevin Pauza, Mark I. Richards, James B. Rogan
A. A method of repairing a defect in an annulus fibrosus of an intervertebral disc, without excising the entire nucleus pulposus of the disc, comprising: inserting an introducer needle having a tip through the annulus fibrosus, injecting an in situ curable, bio-compatible polymerizable or polymeric material composition that includes a cross-linking agent into the disc.
B. The method (above) further including a very long list of drugs, biologics and other additives.
Inventor: Kevin Pauza
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Grant
Filed: October 5, 2009
Issued: March 12, 2013
Assignee: Spinal Restoration, Inc.
Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Grant
Filed: October 5, 2009
Issued: March 26, 2013
Assignee: Spinal Restoration, Inc.
Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
Abstract: A method and kit for treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Grant
Filed: August 17, 2005
Issued: March 26, 2013
Assignee: Spinal Restoration, Inc.
Inventors: Steven I. Whitlock, Brian D. Burkinshaw, Kevin Pauza
A. A method of treating a disc comprising injecting a fibrin sealant into the disc, wherein neither the nucleus pulposus nor the annulus fibrosus has been heated…and wherein the injecting occurs by inserting an introducer needle having a tip into an intra-discal space, inserting a second needle or a polymeric catheter through the introducer needle up to but not beyond the tip of the introducer needle, and injecting the fibrinogen through the introducer needle and injecting the activating compound through the second needle or polymeric catheter, or injecting the activating compound through the introducer needle and injecting the fibrinogen through the second needle or polymeric catheter.
B. The method (above) further including a very long list of drugs, biologics and other additives.
C. A method of treating a disc comprising injecting a fibrin sealant into the disc, wherein neither the nucleus pulposus nor the annulus fibrosus has been heated…and wherein the fibrin sealant does not include a corticosteroid, and wherein normal hydrostatic pressure in the disc is restored or normal disc height is restored or both.
D. The method (above) wherein the injecting occurs by inserting an introducer needle having a tip into the nucleus pulposus, inserting a second needle having a tip into the nucleus pulposus, and injecting the fibrinogen through the introducer needle and injecting the thrombin through the second needle, or injecting the thrombin through the introducer needle and injecting the fibrinogen through the second needle.
Inventor: Kevin Pauza
An apparatus for delivering a biocompatible sealant, comprising: at least two reservoirs for fluids to be delivered, an actuation assembly that causes the fluids to flow out of the reservoir through an exit port in the reservoir, and a pressure monitor coupled to the delivery device to measure pressure within the device.
Inventor: Kevin Pauza.
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: June 26, 2012
Issued: December 27, 2012
Inventors: Brian D. Burkinshaw, Steven I. Whitlock, Kevin Pauza, Mark I. Richards, James B. Rogan
Abstract: A method and kit for treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: October 22, 2010
Issued: September 1, 2011
Inventors: Steven I. Whitlock, Brian D. Burkinshaw, Kevin Pauza, John L. Wheeler, Kevin Thorne
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: October 5, 2009
Issued: September 16, 2010
Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: October 5, 2009
Issued: June 10, 2010
Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlick, Mark I. Richards, James B. Rogan
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: October 5, 2009
Issued: September 16, 2010
Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: October 5, 2009
Issued: June 10, 2010
Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlick, Mark I. Richards, James B. Rogan
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: October 5, 2009
Issued: June 3, 2010
Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
Abstract: A method is effective for treating herniated discs. The method includes (a) surgically remove a herniated portion of disc annulus from a herniated disc, or surgically depressing and holding a herniated portion of disc annulus within original boundaries of the herniated disc, and (b) re-enforcing the surgically treated disc with an effective amount of a biocompatible degradable polymeric compound, such as a fibrin sealant.
Type: Application
Filed: May 24, 2007
Issued: November 27, 2008
Inventors: Kevin Pauza, Brian Burkinshaw, James Rogan
Abstract: Apparatus for delivering biologic sealant device that includes a pressure monitor coupled to the delivery device to measure pressure within the device. A method of treating a disc using the device as well as a kit including the device is described.
Type: Application
Filed: January 5, 2007
Issued: September 13, 2007
Inventors: Mark Richards, Brian Burkinshaw, Kevin Pauza, James Rogan
Abstract: An apparatus for percutaneous delivery of a sealant comprising: at least two fluid reservoirs, an introducer needle having a distal tip that is in fluid communication with at least one reservoir, a fluid delivery tube that is in fluid communication with a second reservoir, wherein the fluid delivery tube has a tip and wherein the fluid delivery tube is configured so that the tip of the fluid delivery tube does not extend past the distal tip of the introducer needle during use.
Type: Application
Filed: January 5, 2007
Issued: August 16, 2007
Inventors: Mark Richards, Brian Burkinshaw, Kevin Pauza, James Rogan, John Wheeler
Abstract: A method and kit for treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: August 17, 2005
Issued: May 18, 2006
Inventors: Steven Whitlock, Brian Burkinshaw, Kevin Pauza
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: August 17, 2005
Issued: May 4, 2006
Inventors: Kevin Pauza, Brian Burkinshaw, Steven Whitlock, Mark Richards, James Rogan
Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Type: Application
Filed: August 17, 2005
Issued: May 4, 2006
Inventors: Brian Burkinshaw, Steven Whitlock, Kevin Pauza, Mark Richards, James Rogan
Disclaimer : Disclaimer: All information presented in this website is intended for informational purposes only and not for the purpose of rendering medical advice. The information contained herein is not intended to diagnose, treat, cure or prevent any disease.
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Disclaimer : Disclaimer: All information presented in this website is intended for informational purposes only and not for the purpose of rendering medical advice. The information contained herein is not intended to diagnose, treat, cure or prevent any disease.
